Q/A with Nobel Laureate Robert H. Grubbs

Robert H. Grubbs' current projects are focused on how to reduce environmental impacts in industry. (GAVIN STERN /  THE STATESMAN)

Robert H. Grubbs’ current projects are focused on how to reduce environmental impacts in industry. (GAVIN STERN / THE STATESMAN)

Robert H. Grubbs, winner of the Nobel Prize for chemistry in 2005 and chemist at California Institute of Technology, came to SBU to present the Distinguished Lecture Series in Science and Engineering, “Catalysis: Green Chemicals and Materials” on Feb. 15, 2013.

Q: Dr. Grubbs, your 2005 Nobel Prize was for a breakthrough in producing synthetic materials, and your lecture today is on green chemistry. But it’s unusual to see ‘synthetic’ and ‘green’ in the same sentence. How do you make a totally synthetic material work well in the environment?

A: You’re trying to make things as environmentally friendly as possible. If we didn’t need any materials we would use wood, but we’re not happy with that so we have to make things. The whole point of green chemistry is to accomplish your goal in the most sustainable way possible.

Q: Is the goal to make these materials able to be broken down by nature?

A: There are all kinds of pieces. There’s the part that when you make stuff, you want to make it as efficiently as possible. You want to make it from sustainable starting materials. You don’t want to make a lot of byproducts when you’re making it. And in the end you want it to be a safe product that you’ve made that can either be broken down or somehow of use to the environment.

Q: You touched on this a bit, but many synthetic chemical pathways currently require rare earth metal catalysts and hazardous solvents. What industrial potential is there for the green alternatives, such as super-critical CO2?

A: There are all kinds of ways of using processes that don’t require solvents, processes that require fewer steps. Supercritical CO2 – there’s all kinds of ways of doing it. People have done studies that show people won’t buy things just because it’s green. It has to be the same price and be just as good. That’s the challenge.

Q: I have noticed a movement towards natural substances, like organic food. Why do people fear chemical processes that are entirely man-made? How do you get past that fear?

A: We’ve got to live. For example, we control pests, otherwise we don’t have food to eat.  The basic strategy is how do you control pests without creating pollution. In each area it’s the same kind of thing –  we have goals to accomplish and we just need to find new ways of doing it.

Q: 20 years from now do you see us using more synthetic materials? Will we recognize what our ‘stuff’ is made of?

A: The population is growing, we’re going to have great demands on our supplies, but we also have to learn how to control CO2 and all the other kinds of things. I think it’s going to be a combination of getting much more efficient processes but also doing it in a way that is more sustainable. That’s the challenge for chemists and all of science.

Q: We have a lot of chemistry students at Stony Brook. What do you want to see them working on when they get into the field?

A: There’s an amazing number of new problems, because we’re going to have to change our starting materials. We have to have new chemistry to be able to use those new starting materials. It’s a really challenging time, which means it’s a great time to be a chemist because there are such huge problems to solve.

Q: What are some of those huge problems that you want to see a breakthrough in?

A: For example, right now most of our starting materials come from petroleum, which is mostly just carbon and hydrogen. Most of the products we use also have oxygen and nitrogen. The chemistry that’s being developed is to put those units in. If you start from bio sources, they usually have too much oxygen and too much nitrogen. The chemistry is the reverse – how do you take it out. There are lots of new processes that you can develop.

There are a tremendous number of exciting problems to work on. I just talked to people here at Stony Brook who are working on ways of purifying water. Water is going to be our very precious resource. There are just many, many problems to solve.

Nobel laureate finally spoke after hurricane postponed event

Come for the laughs, stay for the chemistry.

“It’s good to be here—thanks for the weather,” Robert H. Grubbs, Nobel laureate in chemistry, said.

Neil Edmands, 35, from Hawaii, asks Robert H. Grubbs about the structure of synthetic materials at the Charles B. Wang Center of SBU on Feb. 15, 2013. Gavin Stern / The Statesman

Neil Edmands, 35, from Hawaii, asks Robert H. Grubbs about the structure of synthetic materials at the Charles B. Wang Center of SBU on Feb. 15, 2013. Gavin Stern / The Statesman

More than 100 days after Superstorm Sandy forced a postponement, Grubbs finally presented the Distinguished Lecture in Science & Engineering, “Catalysis: Green Chemicals and Materials” on Feb. 15, 2013.

‘Green chemistry’ is accomplished either by reducing hazardous byproducts or making a product that is more easily broken down by nature.

Students spilled out into the aisles of the Charles B. Wang Center theater for the chance to hear a living legend of synthetic organic chemistry.

Grubbs played the awestruck audience with humble, self-deprecating humor as he led them through a tangle of chemical reactions with his green laser pointer.

“I didn’t really realize I was a ‘green chemist’ until the Nobel committee said I was,” Grubbs said.

Grubbs, the father of Stony Brook University associate professor Robert B. Grubbs, is the Atkins Professor of Chemistry at the California Institute of Technology. He received the Nobel Prize in 2005 along with Richard R. Schrock and Yves Chauvin for devising a catalyst that would speed up “olefin metathesis.”

Grubbs’ work in metathesis revolutionized the production of manmade materials, and the chemical transformations that are now standard in industry—even for companies like Victoria’s Secret.

“One of the highlights of my chemical career,” Grubbs said.

Currently, Grubbs is working on the materials and the chemistry needed to reduce industry’s impact on the environment.

Grubbs’ green chemical processes allow for the production of bio-renewable fuels for cars and jets, crystals that reflect solar radiation, superlight materials for windmills and pheromones that replace harmful pesticides to kill insects.

Making these materials cost effective, however, is a challenge. Grubbs said consumers do not buy green products unless cost and effectiveness are similar to the products they replace.

Grubbs dedicated the final portion of his lecture to the young scientists from all over the globe who work in his laboratory.

“These are the people who are really responsible for everything,” Grubbs said, as he displayed a group photo and introduced each researcher by name. “These are the ones who make it happen.”

Students who attended the lecture said Grubbs succeeded not only in teaching a complicated subject, but also in making the experience itself riveting.

“Dr. Grubbs was absolutely phenomenal. Really over the top,” chemical engineering major Neil Edmands said. “I felt happy to understand at least some of what he was talking about.”

Taurean Dyer, 27, a graduate student from Trinidad studying mechanical engineering at Stony Brook, said he was impressed with Grubbs’ pheromone technology that stops mosquitos from reproducing.

“If he can get that working, that will be a huge boon to the Caribbean and Africa, where dengue is a major cause of death,” Dyer said. “And if we can start making biodiesels at the level Grubbs was talking about, we might hit some big strides, hopefully, in the next 10 years.”

Professor evolves with his research and teachings

Ecology and Evolution Professor Michael Bell has been teaching Stony Brook University students for decades, and constantly learns new things about his field as he goes along. (Photo Credit: Gavin Stern)

Ecology and Evolution Professor Michael Bell, 64, wears a Hawaiian shirt to work every day.

“My wife likes them,” he said, “and I love my wife.” Stacks of books nearly reach to the ceiling of Bell’s windowless basement office. An Alaska license plate hangs above the door. The contents of his adjacent laboratory spill into the office area — fossils, preserved fish and insects, capped vials and weathered metal traps. Asked for a look at his book, “The Evolutionary Biology of the Three-spined Stickleback,” Bell leaps onto his desk. His heels rise out of his sandals as he reaches for the very top shelf.

Before his feet touch the floor, the book is opened to photographs of the stickleback fish. The fish are important, he said, because when a population of sticklebacks moves from saltwater to freshwater, the fish lose their pelvic bones within a few decades. That’s evolution.

Every summer, Bell handpicks students to come up to Alaska to catch and research the three-inch long stickleback fish. In 2005, Bell invited Ericka Kalabaca, then a pre-medical student, to spend five weeks studying the armor structure of the stickleback. Kalabaca, now a family medicine resident at North Shore-LIJ Plainview Hospital, joined Bell’s lab because she wanted a unique research experience. She got it.

In Alaska, the students helped set the traps, picked up the fish and performed in vitro fertilization. Kalabaca described Bell as “very carefree, down to earth, and always there when you needed him.” He was like a father figure to the students, she said. Bell trusted his students and didn’t micromanage, but he expected them to be home for dinner, which he cooked. When the undergraduate students graduated, Bell held a party at his home in Stony Brook.

Bell began researching the three-spined stickleback when, as a young student at UCLA, he called the wrong researcher while looking for a science project. Soon, he was hooked. Bell built his career on the behavior, genetics and evolution of that one tiny lake fish. Eventually, evolutionary biologists realized that the stickleback fish is a good candidate for the “model organism,” alongside mice and rats.

“I wish I could say I was brilliant,” Bell said. “I got lucky.”

Originally from Brooklyn, Bell grew up almost entirely in suburban Los Angeles, near open land. “I always liked living things,” Bell said. “As soon as I was fast enough to catch small bugs, I caught them and put them in a jar.” In particular, Bell liked to catch lizards — alive. But if one died, he might have cut it open to see what was inside.

Bell’s father ran a furniture business and owned a factory while his mother was an office manager in a department store. When Bell was 12, construction began on a freeway near his parent’s house. The excavation of the rock revealed a trove of marine fossils. That experience inspired Bell to become the first scientist in his family. He attended UCLA for his bachelor’s, master’s and doctoral degrees before coming to Stony Brook as an assistant professor in 1978.

Bell has three grown children from his first marriage and one stepchild. His oldest son works for a reinsurance company; his next oldest is an assistant professor of political science at Kansas State University and his daughter, the youngest, is an administrative assistant at a water recycling agency. His stepson is a lawyer. Bell doesn’t get to see his children often, but he’s proud of that. “The real measure of how well your kids have done is they’re too busy to see you,” Bell said.

Bell’s energy may seem limitless to those around him, but that was not always the case. Bell hit a rough patch during the early 1990s. After his book on the stickleback was published, a difficult divorce distracted Bell from his work. “My first wife thought my research was number one,” Bell said. “It wasn’t true.” During that difficult period, Bell said, he wrote poor grant proposals that led to the rejection of his research grants. The lack of funding was devastating. Bell saw the rejection as a sign that he couldn’t do research anymore. He decided to quit.

“He talked about it a lot,” said Jessica Gurevitch, chair of the Department of Ecology and Evolution. “It was very clear he was having a very rough time.” But while Bell was about to give up, members of the department, especially former chair James Rolfe, who had hired him in 1978, pushed for Bell to revise and resubmit the grant proposal. This time, he got funded.

“The decision to pack it in was traumatic,” Bell said. Because he already made peace with the decision to give up research, “it was very hard to resurrect enthusiasm for the work.” The rebuilding process took more than a year.

Around that time, he married his current wife, Cynthia, a novelist who has published more than 50 books, including mystery novels, summer reads and novels for teenage girls. Cynthia is a grounding force for Bell’s scientific enthusiasm. “Mike always wants to talk science. Cynthia talks about other things,” said Peter Park, a former student who came to Bell’s lab as an undergraduate and completed his doctorate with Bell. When Bell and his wife sit together, they hold hands, Park said.

Bell has taught the same two classes, Darwinian Evolution and Chordate Zoology, for decades. “He loves teaching his courses and wants to keep teaching the same ones,” Gurevitch said.

Bell expects a lot from his students, said graduate assistant and doctoral candidate Caitlin Fisher-Reid. She recalled that at the beginning of his class on Darwinian Medicine, Bell informs his undergraduates, “You’re in competition with your classmates.” He reads letters from disgruntled students and explains his expectations. For exams, Bell favors short answer and essay questions over multiple-choice. The average on the first midterm is 60 percent. And yet, his classes almost always fill up.

Unlike most modern biology courses, in which instructors use PowerPoint slides, Bell still lectures from a chalkboard. “I have to run through a bunch of terminology, unfortunately,” Bell said at the beginning of his Darwinian Medicine lecture on phylogeny.

From memory, he fills the board with graphs and evolutionary trees. The small auditorium is full. Eighty students scramble to write down every morsel. Bell frequently stops to pose questions. The students answer back. Once finished with the terminology, Bell demonstrates the common structures of bat and bird wings using his own arm.

“Bell’s teaching style reminds me of high school,” said Siddarth Kuchibhotla, a senior biology undergraduate. “He talks and we have to write it down. Then he waits. It’s more challenging that way.”

Donna DiGiovanni has worked for Stony Brook University since graduating with a biology degree in 1981. She took Bell’s Chordate Zoology course in 1980. “He uses the chalkboard to keep the lecture more personal,” she said. Even though graduate students taught the laboratory component, she said, Bell still came by to assist his undergraduates.

Bell described his early work as “low-hanging fruit” because it was based on what he happened to find in the field. But as molecular biology and the study of genetics advanced, that work became the foundation for more general theories. Eventually, he said, the right people found him based on what they had read in his book. Bell now collaborates with molecular biologists at Stanford to examine the genetic code of the stickleback. But while he’s proud to show that his fossils are used as the best example in biology textbooks, his most enduring final product may be the many young scientists he’s influenced.

“If not for Mike, I would not be where I am,” Park said. Park is now an assistant professor of biology at Nyack College in Rockland County. “He believed in me before I believed in myself.”

Circle Road’s circle breaks

The north entrance to the university will be shuttered from Monday, Nov. 7 until Friday, Nov. 11, to complete a $1.4 million construction project at the intersection of Circle Road and North Entrance Road. Zackary Will, vice president of the Commuter Student Association, described that intersection as “dangerous” because it is on a steep incline. “If you’re coming from below you can’t see the cars above. And if you’re going downhill you can’t see the cars below,” he said.

“Roadway improvements are part of the campus-wide initiative to repair and/or relocate campus roadways in the interest of traffic and pedestrian safety,” said media relations manager James Montalto, in an email. Montalto said that the north entrance construction project will “improve sight lines for drivers.” However, he would not describe the specific changes being made to the roadway to remedy the visibility issue.

Commuter students, though inconvenienced by the closure, are being kept in the loop by Commuter Student Services.

“We keep the students updated on our Blackboard page and various other methods that we use to reach out to commuter students,” said Emily Resnick, senior adviser for commuter student services. “We are doing as much as we possibly can to let them know what’s going on and keep them aware so they’re making changes accordingly.”

In the meantime, students needing to access the northern parking lots can take Toll Road, which is normally closed to traffic.

Paranormal activities on Long Island

Above, members of the Long Island Paranormal Investigators are hard at work. At right, purported photographic evidence of a spirit on a track field. (PHOTO CREDIT: LONG ISLAND PARANORMAL INVESTIGATORS)

Michael Cardinuto is a supervisor at Wendy’s and team leader at The Sports Authority. But late at night, he is “Colonel Cardinuto,” co-founder and leader of the Long Island Paranormal Investigators, or LIPI. His 12 member crew investigates private homes and urban legends, and unlike the Ghostbusters, they do it all for free.
Cardinuto is possessed by a passion for science and a healthy amount of skepticism. “This isn’t an exact science,” he said. “That’s why our group doesn’t charge, because we can’t guarantee it. It’s not like ‘Ghostbusters,’ where you can set a trap and take it away.”

Cardinuto has lived in Ronkonkoma his whole life. As a boy scout, he loved to play hockey and go camping. Early on, Cardinuto struggled with a reading comprehension issue — except when he read stories about ghosts and UFOs.

“When I read them I’d understand them,” he said. He also liked to learn about the local urban legends, such as the “police officer” on Mount Misery Road who would pull over cars — and then turn around to reveal that the back of his head was blown out.

In 2003, Cardinuto dared two of his friends to go into an old psychiatric center. They returned with tales of a paranormal experience. Intrigued, Cardinuto went on the Internet and learned about equipment that could be used to investigate paranormal activity.

Cardinuto’s friend, “Lieutenant Colonel” Rob Levine, was taking a parapsychology course in college. Together, they founded the non-profit Long Island Paranormal Investigators.

According to Cardinuto, there are four different types of hauntings that paranormal investigators encounter. “Residual hauntings” are like a tape playing over and over. The spirit doesn’t know you’re there, Cardinuto said. However, in an “intelligent haunting,” the ghost or spirit can respond to you. A “shadow people haunting” involves black, opaque figures that move very quickly. They avoid light, cameras and the gaze of people. Though shadow people appear human-like, “they’re not of this world.” Cardinuto said, “They were never living as a human.” Finally, there is the “demonic haunting.” These are the most serious, the most involved and the most rare, according to Cardinuto.

“If it’s a demonic haunting you have to get a priest to come in to do an exorcism on the house,” Cardinuto said. “They’re a lot more dangerous cases.”

The LIPI team collects evidence with handheld video cameras, digital and film cameras, tape recorders, EMF meters, Geiger counters and thermometers. They investigate urban legends, as well as private homes and businesses.

“We log down all of our readings and data and publish a report for every urban legend,” Cardinuto said. The team will ask questions of the haunting and see if its instruments pick up any activity. Sometimes, the hauntings can directly communicate with the team by blinking the lights on an instrument — once for yes, twice for no. One member of the team is a psychic, but Cardinuto requires data from his equipment for the final analysis.

For home investigations, clients contact LIPI via its website. After an interview, the team sets up a DVR system in the house as well as other stationary equipment to gather data. The team analyzes the video footage and goes over the data with the client.

“We always offer a follow up investigation,” Cardinuto said. Regular hauntings, and especially intelligent hauntings, can get violent. “If you’re a violent person when you’re living, there’s a good chance when you pass away you’re still going to be violent,”

Cardinuto said. “You can be in a spirit form and you can torment that family by throwing things at them and scratching people and things like that.”

While investigating, the LIPI team reported having been touched, scratched, and in one case, a member had a tape recorder knocked out of his hand.

LIPI does not have the capability to get rid of hauntings, but Cardinuto has attended “house cleansings,” which involve opening all the doorways in the home and burning sage, frankincense and myrrh in every room to smoke out the negative energy. Salt is then sprinkled in all the windows and doorways to keep the energy out. For some intelligent hauntings, a psychic can talk with the haunting and convince it to move “to the other side.” However, since residual hauntings are burned into that specific location, “You can knock down a building, build a new one, and it’s still going to be there,” Cardinuto said.

Currently, LIPI has 12 members and recently held an interview session to take on four more. “Everyone has their own thing they do, everyone plays an important role,” Cardinuto said. In new recruits, Cardinuto looks for people who are driven to enter the field and volunteer time away from their personal lives. To raise money, every member contributes $10 per month. To raise additional funds, LIPI holds presentations (for which they charge a fee), sells merchandise on its website and accepts donations.

Cardinuto has personally spent more than $25,000 to support LIPI. “This is like a college course that doesn’t end,” he said. “You’re paying to be here and getting an education out of it.”

Cardinuto understands that some people think he’s crazy. “There are a lot of people who go skiing and snowboarding, who jump out of airplanes. I think that’s dumb,” he said. “I’m glad that there are skeptics…. If you can prove to a skeptic that the paranormal exists, based on the evidence, and they agree with you, then you know you’ve got them. In this field you need skeptics.”

Construction begins on hotel

Bare dirt replaces 3.7 acres of forest that once stood near the main entrance to the university. By the fall of 2012, a Hilton Hotel will peek over the row of trees that line Shirley Strum-Kenny Drive and Nicolls Road. The university hopes this hotel will benefit its annual 500,000 guests and visitors, but the location has been a source of controversy since plans were first announced in 2009.

“The initial phase of construction is underway,” said Helen Carrano, the university’s director of community relations. “Concrete footings and foundation walls are in progress.”

The final hotel will be five stories high and contain 135 guest-rooms with 5,000 square feet of meeting space. SBHC Private Equity IV, LLC, owned by Stony Brook alumnus Robert J. Frey, is financing the construction and leasing the land from the university. In addition to the benefits of the hotel, the university will receive a minority equity share and $100,000 per year in rent with a 3 percent per year escalation fee. Crescent Hotels & Resorts, LLC, a franchise of Hilton Garden Inn, will manage the hotel.

“I’m a little uncomfortable about the further development of the land. But it will provide benefits for the university,” said Sean Burton, an English and history double major. Burton, a senior,  hopes that the hotel will benefit student clubs and events that rely on out-of-state support, like the I-CON science fiction convention this spring.

However, the forest was previously used as an outdoor laboratory for biology students.

“The loss is, in my opinion, a great one for the university,” said Caitlin Fisher-Reid, a doctoral candidate in the department of ecology and evolution. “The beauty of the forest was its proximity to the Life Sciences research building… It was very easy to design labs that utilized the forest.” Fisher-Reid protested against the proposed hotel at a town hall meeting in 2009. The forest contained a population of the eastern red-backed salamander, which Fisher-Reid was studying for her dissertation. Now that the forest is gone, she isn’t sure the salamanders will be able to find a new territory.

Tim Enright, a fourth year history and anthropology major, is also concerned about the tradeoff for students. “The hotel would be fine to have for conferences but education should take precedence,” he said. “That’s what universities are for.”